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SET7/9 Methyltransferase Inhibitor Screening Assay Kit - 96 Well

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SET7/9 is a MT that acts on various substrates including histone 3 at lysine residue 4 (H3K4), p53, and the transcription factor TAF 10. In Caymans SET7/9 MT Inhibitor Screening Assay the transfer of the methyl group from SAM by SET7/9 to the acceptor peptide (TAF 10) generates SAH, which is rapidly converted to urate and H2O2 using an enzyme mixture provided in the kit. A subsequent reaction between H2O2 and ADHP produces the highly fluorescent compound resorufin.Application/Fluorescence, Application/Inhibitor Screening Assay, Chemical Class/Assay Kits, Chemical Class/Methyltransferase, Research Area/Cancer, Research Area/Chromatin Research, Research Area/Drug Discovery, Research Area/Epigenetics, Research Area/Histone ModificationSynonyms :

434.17 € 434.17 EUR 434.17 €

434.17 €

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